What’s all the fuss about Regenerative Medicine?
Understanding Regenerative Medicine
Explore the concept of regenerative medicine and its role in healing various ailments using the body’s natural processes.
Benefits of Regenerative Medicine
Discover why patients are turning to regenerative medicine for non-invasive treatments with minimal side effects.
How Regenerative Medicine Works
Extraction and Application of Platelet-Rich Plasma (PRP)
Explain the process of obtaining PRP from a patient’s own blood or tissues and its application to promote healing.
Patient Experiences with Regenerative Medicine
Testimonials and Success Stories
Share real-life accounts of patients who have benefited from regenerative medicine treatments, highlighting their positive outcomes.
Future of Regenerative Medicine in Healthcare
Predictions and Trends
Discuss the potential growth and importance of regenerative medicine in future healthcare practices, likening its impact to groundbreaking medical advancements like penicillin.
Training and Implementation in Medical Practice
Integrating Regenerative Medicine
Explore how physicians are incorporating regenerative medicine into their practice through specialized training courses to enhance patient care.
Comparing Regenerative Medicine to Traditional Treatments
Advantages Over Conventional Medicine
Highlight the advantages of regenerative medicine over traditional medical approaches in terms of effectiveness and patient satisfaction.
Conclusion: Embracing Regenerative Medicine
Summarize the potential of regenerative medicine to revolutionize healthcare by offering effective, non-invasive treatments with fewer side effects.
References
Ensure comprehensive citations and references to support claims and information presented about regenerative medicine.
- Published in Blog
Platelet-Rich Plasma Vs Stem Cell Therapy: Who’s Bad?
Platelet-Rich Plasma (PRP) Therapy Explained
Learn how PRP utilizes natural healing mechanisms to enhance tissue repair and manage joint issues like arthritis.
Stem Cell Therapy: A Revolutionary Approach
Explore the potential of stem cell therapy in regenerative medicine and its applications in treating various orthopedic conditions.
Comparing PRP and Stem Cell Therapy
Mechanisms and Applications
Differentiate between PRP and stem cell therapy, highlighting their unique roles in healing and tissue regeneration.
Benefits of Platelet-Rich Plasma (PRP) Therapy
Advantages Over Stem Cell Therapy
Discuss the specific benefits of PRP, such as safety and simplicity, compared to more complex stem cell procedures.
Risks and Considerations with Stem Cell Therapy
Potential Drawbacks
Examine the risks associated with stem cell therapy, including concerns about uncontrolled growth and immune responses.
Conditions Treated with Stem Cell Therapy
Orthopedic Applications
Explore common orthopedic conditions effectively treated with stem cell therapy, including arthritis and joint injuries.
Conclusion: Choosing the Right Treatment Option
Making Informed Decisions
Summarize key points to help patients and healthcare providers make informed choices between PRP and stem cell therapy.
Future of Regenerative Technologies
Trends and Innovations
Look ahead to the future of regenerative medicine, discussing advancements and potential developments in both PRP and stem cell therapies.
References and Further Reading
Ensure comprehensive citations and references to support claims and information presented about PRP and stem cell therapies.
- Published in Blog
The Growth Factor Showdown: Plasma Vs Fibrin
WEDNESDAY, 25 APRIL 2018 / PUBLISHED IN BLOG
Platelet-Rich Plasma (PRP) and Platelet-Rich Fibrin (PRF) have been the subject of numerous speculations regarding their efficacy in facilitating angiogenesis, hemostasis, osteogenesis, and bone growth. The primary reason these platelet products are effective is due to the growth factors they carry. Let’s delve into the specific roles of these growth factors in the healing process.
Growth Factors in Platelet-Rich Plasma
These growth factors play vital roles in PRP and contribute significantly to the healing process:
Platelet-Derived Growth Factor (PDGF)
Regulates cell growth and division, especially in blood vessels, making it crucial for blood vessel reproduction.
Transforming Growth Factor Beta (TGF-β)
Responsible for overall cell proliferation, differentiation, and various other cellular functions.
Fibroblast Growth Factor (FGF)
Plays a key role in wound healing and embryonic development, influencing the proliferation and differentiation of specialized cells and tissues.
Vascular Endothelial Growth Factor (VEGF)
Essential for vasculogenesis and angiogenesis, VEGF restores oxygen supply to cells when it is inadequate and helps create new blood vessels after injury.
Keratinocyte Growth Factor (KGF)
Found during the epithelialization phase of wound healing, KGF stimulates the formation of epithelium immediately after a wound or injury occurs.
Connective Tissue Growth Factor (CTGF)
Functions in cell adhesion, migration, proliferation, angiogenesis, skeletal development, and tissue wound repair.
Platelet-Rich Plasma Rules
A recent study suggests that PRP and its gelled cousin, PRF, differ significantly in the release of these growth factors, which can affect the healing outcome. The study concludes that:
PRP releases significantly higher proteins at earlier time points, which is beneficial for short-term effects.
PRF shows a continual and steady release of growth factors over a 10-day period, making it more beneficial for long-term healing.
Advantages of Platelet-Rich Fibrin Over Platelet-Rich Plasma
PRF has some notable advantages over PRP, including:
- It doesn’t require thrombin and anticoagulants.
- It results in better healing due to its slow polymerization process.
- It aids in hemostasis.
How Platelet-Rich Plasma Differs from Platelet-Rich Fibrin
Platelet-Rich Plasma is produced using a double spin method: a hard spin to separate red blood cells from everything else in the autologous blood, followed by a soft spin to separate the platelets and white blood cells, resulting in PRP, Platelet-Poor Plasma (PPP), and Red Blood Cells.
Platelet-Rich Fibrin is created using a newer method. After the first centrifugation, the middle layer is taken, containing fewer platelets but more clotting factors. This gradually forms into a fibrin network that traps cytokines and is then centrifuged again to result in PRF, a fibrin layer containing platelets and plasma.
What Matters in Healing
When it comes to accelerating healing, the immediate availability of growth factors and cytokines is crucial. PRP may be more effective in this regard due to its immediate release of growth factors, allowing for repeated injections for additional healing factors just days after the initial injection.
Conclusion
Platelet-derived products are still in their infancy. Despite their potential benefits, more research is needed to fully understand their capabilities. If you’re a physician using any or both of these products, we encourage you to share your experiences with us through our contact form.
- Published in Blog
What’s True About Platelet-Rich Plasma For Stretch Marks?
MONDAY, 16 APRIL 2018 / PUBLISHED IN BLOG
Cindy is a career woman. When she became pregnant for the first time, she was torn between prioritizing her work and taking care of her growing body. To avoid drowning in that confusion, she kept herself busy with work all day while snacking during her free time. This led to rapid weight gain. Occasionally, her experienced sister would remind her to apply Bio Oil on her growing tummy before bed, but she was too exhausted to do it regularly. It wasn’t until after she delivered her baby that she realized her folly – her belly now looked like a road map.
What Works for Stretch Marks?
There are a variety of topical treatments, with those containing cocoa butter being trendy, but they hardly affect severe stretch marks. They perform better when used as preventive measures because fully developed stretch marks are rarely skin deep. The stretching occurs in the dermis layer underneath the surface. The inability of the epidermis to keep up with the stretching causes the appearance of deep roads of stretch marks.
One way to “cure” stretch marks, or at least reduce their appearance, is to make the skin surrounding the stretch marks more even with the stretch marks themselves. This can be achieved through various minimally invasive “scarring” technologies like microdermabrasion, microneedling, and CO2 fractional laser.
Platelet-Rich Plasma for Stretch Marks
How Platelet-Rich Plasma Works
Platelets can supply growth factors wherever healing is initiated. So unless healing is initiated or is still ongoing (which is not the case with fully developed stretch marks), the injected Platelet-Rich Plasma may not produce its excellent results.
That’s why in forums you can hear a lot of advice from doctors who claim Platelet-Rich Plasma can’t help stretch marks. In fact, that’d be the first thing I’d say if someone asked me. However, what if we could artificially initiate the healing? Not only in the outer epidermis layer, but also in the underlying dermis layer too? Now, that’s an excellent opportunity to put the growth factors in Platelet-Rich Plasma to good use, wouldn’t you agree?
PRP Microneedling for Stretch Marks
How PRP Microneedling Works
PRP microneedling involves swapping Vitamin C, used in traditional microneedling, with Platelet-Rich Plasma. This is traditionally called a Platelet-Rich Plasma facial because you’re essentially spreading blood components over your face. This is particularly effective for the face, but it can provide even better results for stretch marks.
Getting to the Root of the Problem
With microneedling, tiny holes are punched in both the outer epidermis layer and the inner dermis layer of the skin. These holes are so micro that they restore back to normal within minutes or hours. However, during the time they’re open, a healing response is triggered. Triggering a healing response in the inner dermis layer means there’s going to be some improvement in the stretch marks, as that’s where the source is. The procedure also removes unwanted, half-dead cells from the outer skin, causing the stretch marks to appear less deep.
Accelerated Healing with PRP
PRP accelerates the healing response triggered by the microneedles, and it must do so during the time the holes are open. So immediately after the microneedling, a concentrated gel of PRP is applied and massaged well enough for the platelets to seep through the holes. These platelets first stop the micro-bleeding caused by the microneedles, and then the growth factors in the platelets trigger the production of a substantial amount of collagen. Collagen’s primary role is the replacement of dead skin cells, which means it’ll replace all the dead, broken, and torn skin cells in the entire area. The result is fresh new skin in the areas of the stretch marks, causing them to shrink in size and look more rejuvenated.
Why Platelet-Rich Plasma?
The Healing Power of PRP
Platelet-Rich Plasma is a powerful healing component, initially discovered in 1987. Surgeons found that autologous platelet-rich plasma and red blood cell concentrates diminish the cost of healing for cardiac surgery, meaning faster, efficient, and natural healing for patients. The same force that heals cardiac surgery can also rejuvenate our skin or any other organ in the body. We’re only beginning to uncover the healing potential found in Platelet-Rich Plasma. Studies show that PRP can even heal bones.
PRP vs. Topical Products
It’d be foolish not to use such a potent, natural healing agent for skin rejuvenation purposes. Microneedling seems to be just what Platelet-Rich Plasma needs to exercise its healing powers. It’s much better than stockpiling topical products that might “cure” stretch marks, such as scar creams, retinoids, and peptides.
The Sooner, the Better
Studies show platelets are more efficient when introduced right after wound initiation. The same applies to stretch marks. As soon as you see those marks, it’s better to head straight to the clinic and get a Platelet-Rich Plasma + microneedling session to heal them. The longer you wait, the harder it gets to remove them. So stop experimenting with topical creams—they’re meant to be used as preventive measures.
- Published in Blog
Platelet-Rich Plasma For Bone Healing: Myth or Fact?
WEDNESDAY, 11 APRIL 2018 / PUBLISHED IN BLOG
Platelet-Rich Plasma (PRP) has a proven record for healing soft tissues and other living tissues. But can it actually heal bones? This could mean PRP, when applied to an affected area such as an elbow joint, knee, or backbone area, heals everything within its reach, including bones. Is that really why PRP works? Let’s examine.
Platelet-Rich Plasma for Bone Healing
Bones are not just lifeless matter attached to living tissues. They are as much living as the tissues themselves and are constantly changing. Old bone cells are broken down and replaced with new ones in a three-part process called bone remodeling. This involves resorption (digestion of old bone cells), reversal (birthing of new cells), and formation (new cells turn into fully formed bones).
This process, like other biological processes in the body, requires hormones and growth factors. Some of these include parathyroid hormone (PTH), calcitriol, insulin-like growth factors (IGFs), prostaglandins, tumor growth factor-beta (TGF-beta), bone morphogenetic proteins (BMP), and cytokines. For this discussion, we need to remember only one thing: a large number of cytokines and growth factors are involved in the bone remodeling process. This means we can accelerate the bone remodeling process by supplying these cytokines and growth factors as suggested by various studies.
Why Platelet-Rich Plasma?
Autologous Platelet-Rich Plasma (PRP), being completely “whole and natural,” can more closely simulate a highly efficient in-vivo situation than anything else made up of artificial recombinant proteins. In PRP, we take advantage of the biological benefits of growth factors whose functions we know as well as those we do not know yet. From the 15+ factors we know are in PRP, including platelet-derived growth factor (PDGF), transforming growth factor-beta (TGF-beta), platelet factor 4 (PF4), interleukin 1 (IL-1), platelet-derived angiogenesis factor (PDAF), vascular endothelial growth factor (VEGF), epidermal growth factor (EGF), platelet-derived endothelial growth factor (PDEGF), epithelial cell growth factor (ECGF), insulin-like growth factor (IGF), osteocalcin (Oc), osteonectin (On), fibrinogen (Fg), vitronectin (Vn), fibronectin (Fn), and thrombospontin-1 (TSP-1), we’re supplying a “holistic” set of nutrients for healing that cannot be mimicked by those obtained artificially.
PRP: Organic Fertilizers for the Body
The difference with PRP is akin to adding chemical fertilizers versus organic fertilizers to plants. Chemical fertilizers are rich in essential nutrients that we know are needed for crops. On the other hand, organic fertilizers supply nutrients not only to the plants but also to the soil, improving the soil structure and tilth, water-holding capacity, reducing erosion, and promoting slow and consistent release of nutrients to the plants. Clearly, organic fertilizers are better, aren’t they?
Platelet-Rich Plasma is like organic fertilizers for our body.
Bonus: Strong Antimicrobial Properties
PRP’s healing function also has synergistic antimicrobial properties. A new study confirms that using Platelet-Rich Plasma in surgeries may have the potential to prevent infection and reduce the need for costly post-operative treatments. That’s a nice bonus for the organic fertilizer of our bodies. Perhaps there are more benefits to discover.
Conclusion
The scope of Platelet-Rich Plasma is growing as the scientific community continues to unearth its inherent properties. PRP is an unignorable and unavoidable component of healing.
- Published in Blog
Why Should you Include PRP In Your Medical Practice?
MONDAY, 26 MARCH 2018 / PUBLISHED IN BLOG
Platelet-Rich Plasma (PRP) has been a lifesaver for many medical practices, reigniting physicians’ passion for medicine. Not only is it 100% derived from the patient’s own body, but it is also natural and comes with minimal side effects. PRP can treat a wide range of medical conditions, often outperforming other treatment options.
The Simplicity of PRP
One of the most compelling reasons to include PRP in your practice is its simplicity. With an initial investment of about $1000, you can start offering PRP therapies. The equipment is relatively inexpensive and pays for itself quickly.
Long-Term Popularity
PRP is not a passing trend. It has been gaining popularity for years and shows no signs of slowing down. The market for PRP therapies is expected to reach nearly $500 million within the next decade, with an annual growth rate of 12.5% since 2015.
High Patient Satisfaction
Patient satisfaction is another significant advantage. In certain cases, satisfaction rates have been as high as 95%. Patients are often surprised by the efficacy of PRP, believing that their conditions could not be reversed or halted without side effects, downtime, and invasive surgeries.
Meeting the Growing Demand
Now is the time to start including PRP in your practice. The supply is low, but demand is booming. PRP therapies hold great promise, especially when combined with other treatments to increase efficacy. Since no standard has been established, you have the opportunity to set these standards yourself.
Be a Pioneer in PRP Therapy
It is vital that more doctors utilize PRP therapy to become pioneers in this field. PRP has the potential to revolutionize medicine, and missing out would not be a smart option.
Versatility Across Specialties
PRP can be utilized in almost every field and specialty, from sports medicine and pain management to skin rejuvenation, hair care, and even urology. Most physicians who use PRP treatments have also seen higher patient retention rates.
Conclusion: A Smart Addition to Your Practice
So, is there a legitimate reason not to add PRP to your practice? With its simplicity, high patient satisfaction, growing popularity, and versatility, PRP is a smart addition to any medical practice. Start offering PRP treatments and watch your practice thrive.
- Published in Blog
Three popular PRP Treatments for Skincare
THURSDAY, 15 MARCH 2018 / PUBLISHED IN BLOG
Thousands of skincare centers across the nation provide at least one kind of PRP treatment. However, most do not go any further than micro-needling with a topical solution. This is mainly because it is far simpler than all other methods, and it is incredibly popular. However, it would make more sense for many practices that have invested in equipment to add PRP injections as well.
PRP Is Growing Substantially
Regardless of what is being treated, the protocol for obtaining PRP is the same: draw the blood, place it in the centrifuge, and then extract the PRP from the rest of the material. This simplicity, combined with PRP’s vast usability, can create significant and mind-blowing advances in modern medicine.
This includes skincare, as the PRP obtained from patients can be used in a plethora of ways. Here are a couple of examples of what can be performed by dermatologists and plastic surgeons worldwide.
Skin Augmentation
Adding a topical solution of PRP combined with microneedling can help regenerate dying skin cells and make the skin feel soft. Although this will probably work for most clients, many might want more. For instance, if you want to plump up the face, injecting PRP into the dermis can provide both beauty and a healing process.
If you want to create volume, you will need a filler. One way to do this is by using a Platelet-Poor Plasma filler (PPP), often left over from the PRP process. You can also use Hyaluronic Acid. A combination of these with PRP has been known to provide wonderful results, with some clinicians boasting a 100% success rate.
Vitiligo Correction
Many companies spend millions of dollars to find out how to turn defective cells healthy again, often looking into DNA technology. However, simply utilizing PRP may provide the same results. Some studies have shown that adding CO2 laser therapy for correcting vitiligo to a PRP treatment can increase its effectiveness by four times. This can also be beneficial in other areas, such as correcting wrinkles and even acne scars. So combining PRP treatments with conventional therapies can boost the effects tremendously.
If PRP can help boost the effects of lasers, it may also boost the effects of other skin therapies. This is a great opportunity to continue the work you do, but this time more effectively due to a simple method. Hundreds of skincare facilities are already providing this for their clients.
Hair Rejuvenation
Mesotherapy is a common treatment that utilizes microinjections to deliver medication throughout the skin’s surface. This procedure has provided great quality results by adding peptides and vitamins to the mix. However, one of the best ways to incorporate this into your practice is by using PRP therapy.
Mesotherapy can also be used to provide an even amount of PRP all over the body, including the face, neck, hands, etc. This helps to rejuvenate the skin and reduce wrinkles, discoloration, and stretch marks. However, it works best for hair loss treatments. In fact, adding PRP to mesotherapy has exceeded the industry’s expectations.
This is why PRP therapy is something every skincare clinic should offer. Since hair loss affects both men and women, it is important to make your treatments as effective as possible. Your patients will benefit from it, and satisfaction will rise. Is there any other reason to put it off?
“But I Never Heard Of Them!”
Some of these treatments and combinations are incredibly new, so new that many might not have heard of them before. This is why signing up to use them as soon as possible is vital. This way, you can be a step ahead of the competition when it comes to providing great services.
The demand for PRP is only growing over time, and the sooner you can get on board, the better off your practice will be. If you are interested in learning more about PRP therapy or checking out our line of PRP equipment, visit the Adimarket website.
PRP provides more effective treatments in less time, for less money, and with more satisfaction. Many practices have put their trust in this treatment and have been reaping the long-term benefits. PRP is here to stay. Are you ready to seize the potential of this great medical revolution.
- Published in Blog