Some people believe that stem cells can achieve this, but studies show it’s unlikely in most cases. While minimal growth may be observed a year after treatment, full cartilage replacement is rare.
Limited Regenerative Capacity of Cartilage
Cartilage has limited regenerative capacity, and current pharmacological treatments offer only symptomatic relief. Patients who don’t respond to conventional therapies may undergo surgical procedures like arthroplasty or total joint replacement.
Stem Cells for Cartilage Repair
Stem cells from various tissues have been used over the last two decades to treat osteoarthritis and bone damage. They primarily aid in cartilage repair but often fail to fully replicate native tissue properties.
Potential of Stem Cell Therapies
Stem cell therapies using MSCs or iPSCs have shown promise in clinical settings. iPSCs, in particular, offer patient-specific regeneration potential.
Understanding Cartilage and Its Damage
Cartilage is crucial for joint function, providing cushioning and flexibility. Damage, whether from trauma or conditions like osteoarthritis, reduces its effectiveness.
Treatment Options for Cartilage Damage
Current treatments focus on symptom relief or joint replacement for severe cases.
How Stem Cells Can Help
Stem cells, sourced from bone marrow or fat, can develop into chondrocytes and aid in reducing inflammation and stimulating repair.
Challenges in Cartilage Regrowth
Cartilage’s complex structure requires more than just cell injection for effective regeneration. Scaffold-like structures are being researched for better outcomes.
Mechanism of Stem Cell Action
Stem cells work through anti-inflammatory processes and regeneration stimulation, though they do not transform into different tissues.
Role of ISSCA in Advancing Regenerative Medicine
The ISSCA promotes standards and research in regenerative medicine, offering certifications and advancing the field’s understanding.
